Contextual Effects in Nonpharmacologic Therapies for Knee Osteoarthritis Pain
- RRS Education
Achy, ‘grumpy’, osteoarthritic knees are very common and can be an activity-limiting annoyance for many patients. Our job as clinicians is to help them manage or eliminate discomfort and maximize function. This can be accomplished via the manual treatments or electro-modalities we offer, as well as the rehab and exercise guidance we provide. This week’s Review looks at the contribution of contextual effects in clinical outcomes from nonpharmacologic therapies for knee OA…the results may surprise you!
Knee osteoarthritis (OA) is characterized by pathological damage to the articular cartilage, meniscus and subchondral bone with osteophyte formation and synovial proliferation. Current treatments attempt to decrease clinical symptoms experienced by patients, which include pain and functional limitations. Effective first line treatment for knee OA includes nonpharmacological and nonsurgical therapies, however patients generally underutilize these interventions
In order to understand the total therapeutic effect of treatment for knee OA, an understanding of both the direct physiological and contextual effects of treatment is required. Examples of contextual factors include the placebo effect, changes attributable to natural history, and effects of co-therapies. Gaining a deeper understanding of this will help improve the management of knee OA.
This systematic review is a first attempt to quantify the role of contextual factors in nonpharmacological, nonsurgical treatments for knee OA patients, comparing baseline and follow-up pain outcomes for active and placebo treatment groups…enjoy!
THIS WEEK'S RESEARCH REVIEW: “Contextual Effects in Nonpharmacologic Therapies for Knee Osteoarthritis Pain”
This paper was published in Osteoarthritis and Cartilage (2020) and this Review is posted in Recent Reviews, Knee, Osteoarthritis and the 2021 Archive.